
Dr. Senthil Kumar D.
Scientist
M.V.Sc., Ph.D., Veterinary Pathology
Email : senthil[dot]d[at]icar[dot]gov[dot]in
Achievements
- Received ICAR-Jawaharlal Nehru Award for P.G. Outstanding Doctoral Thesis Research in Agricultural and Allied Sciences - 2018 in Animal Science category.
- NAIP International training on Stem cell Research, Rutgers – The State University of New Jersey, USA, 4th nov 2013 – 4th Feb 2014.
- Participated in International training workshop on Modelling pathogen prevalence and risk in livestock production, Anand Agricultural University, Anand, July 10-13th, 2013.
- Participated in a 21 days ICAR sponsored winter school training titled “Basic techniques in Solid Phase peptide synthesis and application of synthetic peptides in animal disease diagnosis and research” held at Division of Animal Biotechnology, IVRI, Bareilly, UP during 22nd September to 12th October 2010.
Publication
- MK Pandey, K Rajukumar, D Senthilkumar, S Kombiah, S Shrivas, VP Singh. “Age related changes in lymphocyte sub-populations in peripheral blood of healthy weaned piglets” Indian Journal of Veterinary Pathology (2019) 43 (1): 23-27.
- Senthilkumar, D., K. Rajukumar, Manoj Kumar, S. Kalaiyarasu, D. Shrivastava, M. Katare, D. D. Kulkarni, and V. P. Singh. "Porcine reproductive and respiratory syndrome virus induces concurrent elevation of High Mobility Group Box-1 protein and pro-inflammatory cytokines in experimentally infected piglets." Cytokine 113 (2019): 21-30.
- Senthilkumar, D., K. Rajukumar, A. Sen, M. Kumar, D. Shrivastava, S. Kalaiyarasu, S. Gautam, F. Singh, D. D. Kulkarni, and V. P. Singh. "Pathogenic characterization of porcine reproductive and respiratory syndrome virus of Indian origin in experimentally infected piglets." Transboundary and emerging diseases (2018) 65(6): 1522-1536.
- Senthilkumar D, Suguna Rao, M.L. Satyanarayana, P.G. Pradeep Kumar and N. Anitha “Ameliorative efficacy of citrus oil in aflatoxin induced changes in lymphoid organs in broilers -A pathomorphological evaluation” Indian Journal of Animal Research (2018) 52(10) • 1462-1468.
- Sandeep Kumar Dash, Manoj Kumar, Jag Mohan Kataria, Shanmugasundaram Nagarajan, Chakradhar Tosh, Harshad V Murugkar, K Rajukumar, S Kalaiyarasu, D Senthil Kumar, Diwakar D Kulkarni. “Induction profiles of mRNA of toll like receptors and cytokines in chickens pre-exposed to low pathogenic avian influenza H9N2 virus followed by challenge with highly pathogenic avian influenza H5N1 virus” Microbial pathogenesis (2018) 117: 200-205.
- Dhanapal Senthilkumar, Rajukumar Katherukamem, Kezhedath Jeena, Semmannan Kalaiyarasu, Kumar Manoj, Shrivastava Deepali, Farooqui Hina Bano, Diwakar Kulkarni and Vijendra Pal Singh. “Pulmonary Alveolar Macrophages Reveal Higher Basal Cytokine mRNA Expression than Peripheral Blood Leucocytes in Healthy Piglets” Journal of Animal Research (2017) 7(4): 629-634.
- B R Das, M Kumar, H V Murugkar, S Nagarajan, D Senthil Kumar, S Kalaiyarasu, D D Kulkarni and C Tosh. Experimental inoculation of a crow derived influenza A (H5N1) virus in chickens and its pathological and genetic characterization. Indian Journal of Animal Sciences (2016) 86 (3): 238–242.
- YT Redda, G Venkatesh, S Kalaiyarasu, S Bhatia, D Senthil Kumar, S Nagarajan, A Pillai, S Tripathi, DD Kulkarni, SC Dubey. “Expression and purification of recombinant H5HA1 protein of H5N1 avian influenza virus in E. coli and its application in indirect ELISA” Journal of Immunoassay and Immunochemistry (2016) 37(4):346-358.
- Kulkarni, D. D., G. Venkatesh, C. Tosh, P. Patel, A. Mashoria, V. Gupta, S. Gupta and Senthil Kumar D. "Development and Evaluation of Recombinant Nucleocapsid Protein Based Diagnostic ELISA for Detection of Nipah Virus Infection in Pigs." Journal of immunoassay & immunochemistry (2016) 37(2): 154-156.
- Kalaiyarasu, Semmannan, Manoj Kumar, Dhanapal Senthil Kumar, Sandeep Bhatia, Sandeep Kumar Dash, Sushant Bhat, Rohit K. Khetan, and Shanmugasundaram Nagarajan. "Highly pathogenic avian influenza H5N1 virus induces cytokine dysregulation with suppressed maturation of chicken monocytederived dendritic cells." Microbiology and immunology (2016) 60(10): 687-693.
- Kalaiyarasu, Semmannan, Sandeep Bhatia, Niranjan Mishra, Richa Sood, Manoj Kumar, D. Senthil Kumar, Sushant Bhat, and M. Dass Prakash. "Elevated level of pro inflammatory cytokine and chemokine expression in chicken bone marrow and monocyte derived dendritic cells following LPS induced maturation." Cytokine (2016) 85: 140-147.
- D Senthil Kumar, Suguna Rao, M. L. Satyanarayana, PG Pradeep Kumar, and N. Anitha. "Amelioration of hepatotoxicity induced by aflatoxin using citrus fruit oil in broilers (Gallus domesticus)." Toxicology and industrial health (2015) 31(11): 974-981.
- Dhanapal, Senthil kumar, Suguna Rao, Pradeep Kumar Palahally govindaraju, Ravikumar Hukkeri, and Karikalan Mathesh. "Ameliorative efficacy of citrus fruit oil in aflatoxicosis in broilers: a growth and biochemical study." Turkish Journal of Veterinary and Animal Sciences (2014) 38(2): 207-211.
- Kulkarni, D. D., C. Tosh, G. Venkatesh, and D. Senthil Kumar. "Nipah virus infection: current scenario." Indian Journal of Virology (2013) 24(3): 398-408.
- Kamboj A, Raut AA, Senthilkumar D, Ranaware P, Rajukumar K, Mishra A, Kulkarni DD Amplification and Cloning of Full length ‘S’ Segment of Crimean-Congo Hemorrhagic Fever Virus from Hyalomma ticks infesting cattle in Gujarat, India. Journal Veterinary Public Health (2013) 11 (2): 141-14.
- Senthilkumar D, Suguna Rao, M L Satyanarayana, S M Byre Gowda, P G Pradeep Kumar and N Anitha. Effect of herbal oil, toxin binder and their combination during induced aflatoxicosis in broilers: Growth and biochemical study. Indian Journal of Veterinary Pathology, (2012) 36 (1): 64-68.
Popular Articles
- Senthilkumar D, Manoj Kumar, S. Kalaiyarasu, R. Sridevi, G. Venkatesh (2012). Amelioration methods of Mycotoxins in poultry. Poultry line, 12 (10): 46-50 (pp 141)
- M. Karikalan, D. Senthilkumar, S. Kalaiyarasu, R. Gokulakrishnan. (2013). West nile fever, a potential zoonotic threat. Poultry world (pp 142).
- A. Elamurugan, M. Karikalan, S. Kalaiyarasu, D. Senthilkumar. (2013). Immunosuppression, a potential threat to poultry industry. Poultry world, May. Page 30-32. (pp 144)
- S. Kalaiyarasu, D. Senthilkumar, A. Elamurugan, M. Karikalan and K. Rajkumar. (2013). Effective salmonella control in poultry by alternative strategies. Poultry World, June. Pages 38-39. (pp 145)
- A. Elamurugan , M. Karikalan, S. Kalaiyarasu, D. Senthilkumar. (2013). Importance of avian MHC in poultry health and production. Poultry world, July. Page 36-37. (pp 146)
- S. Kalaiyarasu, Senthilkumar D, Manoj Kumar, P. Sankar, A. Elamurugan and M. Karikalan (2013). Cytokines as potent therapeutic agent and vaccine adjuvant in poultry. Research News For U (RNFU) ISSN: 2250 –3668, Vol. 10, pages 110-115.(pp 147)
- S. Kalaiyarasu, K. Karthik, D. Senthil Kumar, Manoj Kumar and P. Sankar (2013). Virus-Like Particles: A future candidate vaccine in livestock and poultry. Research News For U (RNFU) ISSN: 2250 –3668, Vol. 11, pages 120-123.(pp 148)
- Senthilkumar D, Kalaiyarasu S, Karikalan M, Monalia Sahoo, Pradeep Kumar ay, Elamurugan A, Herbal feed additives and its use in Poultry. Poultry World, April. Page 16-17. (pp 149)
- S. Kalaiyarasu, G. Venkartesh, Manoj Kumar and D. Senthil Kumar (2014). TLR ligands: A novel adjuvants for poultry vaccines. Poultry World, February. Pages 41-42.
- S. Kalaiyarasu, D. Senthil Kumar, A. Elamurugan, M. Karikalan and K. Rajkumar. (2013). Effective salmonella control in poultry by alternative strategies. Poultry World, June. Pages 38-39.
- S. Kalaiyarasu, Manoj Kumar and D. Senthil Kumar. (2013). Biosecurity, a measure to minimize the infectious threats in poultry industry. Poultry Line, April. Pages 47-50.
- S. Kalaiyarasu, D. Senthil Kumar, Manoj Kumar, P. Sankar, A. Elamurugan and M. Karikalan (2013). Cytokines as potent therapeutic agent and vaccine adjuvant in poultry. Research News For U (RNFU) ISSN: 2250 –3668, Vol. 10, pages 110-115.
- S. Kalaiyarasu, K. Karthik, D. Senthil Kumar, Manoj Kumar and P. Sankar (2013). Virus-Like Particles: A future candidate vaccine in livestock and poultry. Research News For U (RNFU) ISSN: 2250 –3668, Vol. 11, pages 120-123.
Oral Presentations
- Patel Priyanka, Tawani Arpita and Senthil kumar D (2012) Comparison of methods for purification of Recombinant nucleocapsid protein of nipah virus and its application in Diagnosis: National Virology Conference, 23rd to 25th January 2012, VSBT, Baramati. (pp 162)
- G. Venkatesh, A.Pillai, N.Kosariya, D. Senthil Kumar, S. Bhatia, A. Pateriya, R.Sood, D. D. Kulkarni and J.M.Kataria (2012). Development and characteriz- ation of MAbs against an Indian Isolate of H5N1 AIV. Presented at XXI National Conference of Indian Virological Society at IVRI Campus,Mukteswar, Uttarakhand India , Nov. 8-10,2012 (pp 163 - 164)
- Senthil Kumar, D., Venkatesh, G., Patel, P., Behera, P., Tawani, A., Tosh,C. and DD Kulkarni. 2012. Optimization of taqman Real-time RT-PCR for detection of Nipah virus. Presented at12th Indian Vety. congress & XIX annual conference of IAAVR at CVSc & AH., Mhow in April 20-21, 2012. (pp 165-166)
- Rajukumar K, Nagarajan S, Senthil kumar D and D D kulkarni. 2011. Swine exotic Diseases and their implications for trade. Presented at National Seminar on Status and scope of pig farming in India- an Appraisal at Post graduate Research Institute in Animal Sciences, Kattupakkam, Tamilnadu in 2011.(pp 167-168)
Trainings Attended
- MDP on PME of Agricultural Research Project from 17th - 22nd December, 2018 at NAARM, Hyderabad.
- Skill Development in cell Culture & Virus Handling Techniques from 12th -21st Feb. , 2019 at Indian Veterinary Research Institute, Izatnagar, Bareill.
- International training cum Collaborative Research programme on Induced Pluripotent Stem cells at Rutgers – The State University of New Jersey, USA from 3rd NOV 2013 to 4th Feb 2014 sponsored by NAIP, ICAR, New Delhi.
- ICAR sponsored winter School on Basic Techniques in solid phase peptide synthesis and applications of synthetic peptides in animal disease diagnosis and research from 22nd September, 2010 to 12th October, 2010 at Indian veterinary research Institute (IVRI), Izatnagar, U.P.
- ICAR sponsored short course on “Open Source Software/Free software (OSS/FS) tools in development of agricultural information and communication management system” from 14th – 23rd September, 2011 at Central Institute for Research on Goats, Makhdoom, U.P.
Training Manuals
- Training Manual. 2014. Eds. FAO-sponsored International Workshop cum Training Programme on HA - HI for Avian Influenza diagnosis organized at HSADL, IVRI, Bhopal from 11-13 Feb. 2014.
- Training manual for International training program for Nepal on Molecular techniques for diagnosis and characterization of Avian Influenza held 16th Jan to 5th Feb 2014.
- Training Manual for ASEAN Indian cooperation program on ‘Conventional and molecular techniques for diagnosis of Trans boundary animal diseases held during 18th Feb to 7th March 2014.
Co-Investigator
- Deployment of nucleic acid and Elisa based diagnostic tests to determine incidence of porcine reproductive and respiratory syndrome (PRRS) in the North East and evaluation of the prospects of a potential candidate vaccine against the disease. (DBT funded).
- Development and evaluation of referral group specific and subtype specific diagnostic reagents for avian influenza.
- Evaluation of H9N2 virus induced alteration in the progression of H5N1 virus infection in chickens.
- Surveillance of Porcine reproductive and respiratory syndrome virus infection and Swine influenza (H1N1). (Institute service project on Surveillance of exotic and emerging animal diseases in Indian and imported livestock & poultry and their products) (Co-Investigator).
- NABARD funded project titled “Development of an immuno-chromatographic test for the diagnosis of avian influenza virus infections in chicken”,(Co-Investigator).
Equal Opportunity for Persons with Disabilities
In accordance with the provisions of the Right of Persons with Disabilities Act, 2016 and Rules, the institute strives to provide opportunities and facilities to persons with disabilities to participate, perform and excel in their work on an equal basis in everyday life.